Day :
- Nanoparticles | Applications of Nanotechnology | Nanoscience and Technology | Nanostructures | Nanoelectronics | Material Science | Nanomaterials | Nanochemistry | Nanophotonic
Location: Webinar
Session Introduction
Delia Teresa Sponza
Dokuz Eylül University, Turkey
Title: Removal some endocrine-disrupting compounds by N-doped BiOBr nanoparticle under solar ligth
Biography:
Delia Teresa Sponza is currently working as a professor at Dokuz Eylül University, Department of Environmental Engineering. Scientific study topics are; Environmental engineering microbiology, Environmental engineering ecology, Treatment of fluidized bed and activated sludge systems, Nutrient removal, Activated sludge microbiology, Environmental health, Industrial toxicity and toxicity studies, The effect of heavy metals on microorganisms, Treatment of toxic compounds by anaerobic / aerobic sequential processes, Anaerobic treatment of organic chemicals that cause industrial toxicity and wastewater containing them, Anaerobic treatability of wastewater containing dyes, Treatment of antibiotics with anaerobic and aerobic sequential systems, Anaerobic and aerobic treatment of domestic organic wastes with different industrial treatment sludges, Treatment of polyaromatic compounds with bio-surfactants in anaerobic and aerobic environments, Treatment of petrochemical, Textile and olive processing industry wastewater by sonication, Treatment of olive processing industry wastewater with nanoparticles and the toxicity of nanoparticles. She has many international publications.
Abstract:
Some endocrine-disrupting compounds like 17β-estradiol, 17α-ethinylestradiol and 4-tert-octylphenol was removed from the surface waters using the N-BiOBr nanocomposite prepared under laboratory conditions. N doping on BiOBr improved the specific surface area and the photocatalytic activity of N-BiOBr. This phenomenon also decreased excessively the acute and chorinic toxicity originating from the 17β-estradiol, 17α-ethinylestradiol and 4-tert-octylphenol. The effects of N percentage removals of the removals of endocrine-disrupting compounds and activity on NBiOBr semiconductor was researched. The effects of N-BiOBr nanocomposite concentrations (0,5, 1, 1,5 and 2 mg/L), the effects of N percentages ( 2%,4%,6%,10%,15%) the effects of sun ligth power ( 1, 2, 4, 7 and 9 W/m2) and contacting times (10, 20, 30 and 40 min) on the of mineralization of endocrine-disruptings were studied. The toxicities performed by V. Fischeri and D. magna showed that the toxicities decreased from 98% to 8% at N-BiOBr nanocomposite concentration of 1,5 mg/l,at a N percentage of 10% after a sun ligth power of 4 W/m2 ana afte 30 retention time under sunligth. By doping BiOBr with N an effective photocatalytic removal process was tedected. Under optimized conditions; 17β-estradiol, 17α-ethinylestradiol and 4-tert-octylphenol were photocatalically removed with yield as high as 99%, 98% and 97%,respectively.
Sabu Thomas
Mahatma Gandhi University, India
Title: Circular economy: New opportunities in sustainable nano materials and polymer bionanocomposites
Biography:
Sabu Thomas is currently Vice Chancellor of Mahatma Gandhi University, Kottayam, India. Prof. Thomas is a highly committed teacher and a remarkably active researcher well-known nationally and internationally for his outstanding contributions in polymer science and nanotechnology. He has published over 1200 research articles in international refereed journals. And has also edited and written 165 books with an H-index of 122 and total citation of more than 72,000. He has received a large number of international and national awards and recognitions. Under the leadership of Prof. Thomas, Mahatma Gandhi University has been transformed into a top University in the country where excellent outcomebased education is imparted to the students for their holistic development.
Abstract:
Green chemistry started for the search of benign methods for the development of nanoparticles from nature and their use in the field of antibacterial, antioxidant, and antitumor applications. Bio wastes are ecofriendly starting materials to produce typical nanoparticles with well-defined chemical composition, size, and morphology. Cellulose, starch, chitin and chitosan are the most abundant biopolymers around the world. All are under the polysaccharides family in which cellulose is one of the important structural components of the primary cell wall of green plants. Cellulose nanoparticles (fibers, crystals and whiskers) can be extracted from agro waste resources such as jute, coir, bamboo, pineapple leafs, coir etc. Chitin is the second most abundant biopolymer after cellulose, it is a characteristic component of the cell walls of fungi, the exoskeletons of arthropods and nanoparticles of chitin (fibers, whiskers) can be extracted from shrimp and crab shells. Chitosan is the derivative of chitin, prepared by the removal of acetyl group from chitin (Deacetylation). Starch nano particles can be extracted from tapioca and potato wastes. These nanoparticles can be converted into smart and functional biomaterials by functionalization through chemical modifications (esterification, etherification, TEMPO oxidation, carboxylation and hydroxylation etc) due to presence of large amount of hydroxyl group on the surface. The preparation of these nanoparticles includes both series of chemical as well as mechanical treatments; crushing, grinding, alkali, bleaching and acid treatments. Transmission electron microscopy (TEM), scanning electron microscopy (SEM) and atomic force microscopy (AFM) are used to investigate the morphology of nanoscale biopolymers. Fourier transform infra-red spectroscopy (FTIR) and x ray diffraction (XRD) are being used to study the functional group changes, crystallographic texture of nanoscale biopolymers respectively. Since large quantities of bio wastes are produced annually, further utilization of cellulose, starch and chitins as functionalized materials is very much desired. The cellulose, starch and chitin nano particles are currently obtained as aqueous suspensions which are used as reinforcing additives for high performance environment-friendly biodegradable polymer materials. These nanocomposites are being used as biomedical composites for drug/gene delivery, nano scaffolds in tissue engineering and cosmetic orthodontics. The reinforcing effect of these nanoparticles results from the formation of a percolating network based on hydrogen bonding forces. The incorporation of these nano particles in several bio-based polymers have been discussed. The role of nano particle dispersion, distribution, interfacial adhesion and orientation on the properties of the ecofriendly bio Nanocomposites has been carefully evaluated.
Delia Teresa Sponza
Dokuz Eylül University, Turkey
Title: Preparation of TiO2 /CdS/GO/Pt nanocomposite to produce methane from waste CO2
Biography:
Delia Teresa Sponza is currently working as a professor at Dokuz Eylül University, Department of Environmental Engineering. Scientific study topics are; Environmental engineering microbiology, Environmental engineering ecology, Treatment of fluidized bed and activated sludge systems, Nutrient removal, Activated sludge microbiology, Environmental health, Industrial toxicity and toxicity studies, The effect of heavy metals on microorganisms, Treatment of toxic compounds by anaerobic / aerobic sequential processes, Anaerobic treatment of organic chemicals that cause industrial toxicity and wastewater containing them, Anaerobic treatability of wastewater containing dyes, Treatment of antibiotics with anaerobic and aerobic sequential systems, Anaerobic and aerobic treatment of domestic organic wastes with different industrial treatment sludges, Treatment of polyaromatic compounds with bio-surfactants in anaerobic and aerobic environments, Treatment of petrochemical, Textile and olive processing industry wastewater by sonication, Treatment of olive processing industry wastewater with nanoparticles and the toxicity of nanoparticles. She has many international publications.
Abstract:
XRD results showed that TiO2 exhibited crystalline properties ana the peaks at 2θ values of 25.63°, 37.5° and 48.4° can be indexed to the (102), (005) and (200) planes of anatase titania. The XRD emissions from the rutile phase showed that TiO2 disappear in the TiO2 /CdS nanocomposite since anatase from is is dominated in TiO2 . Vey low platinum signals was detected from TiO2 /CdS/Pt since the platinum percentage is low. HR-TEM image of the TiO2 /CdS nanocomposite exhibited that it was accumulated on a copper grid. SEM images exhibited that Pt nanoparticles are homogeneously dispersed over GO. HAADF images of the TiO2 /CdS/rGO/Pt nanocomposite exhibited that both Pt and TiO2 /CdS nanoparticles are supported on the surface of GO. The effcts of increasing TiO2 /CdS/GO/Pt nanocomposite concentration (0,1;0,2;0,5 and 1 mg/l), GO percentages ( 5%, 10%,15%,20%), sunligth powers( 1 W/m2; 3, 5 , 10 and 15 W/m2), sunligth duration ( 10 min,20,40,50 and 70min) on the methane production from waste CO2 was investigated. Furthermore, the effects of waste CO2 concentrations on the methane production was studied. A cost analysis was performed for methane production from CO2 . After 50 min illumination time at a 0,5 mg/l TiO2 /CdS/GO/Pt nanocomposite dose at a GO percentage of 10%, at a sunligth power of 1 W/ m2 from 10 mg/l CO2 gas 35 mg/day CH4 gas was produced.
R.A. Ilyas
Universiti Teknologi Malaysia, Malaysia
Title: Nanocellulose: From fundamentals to advanced materials
Biography:
R.A. Ilyas is a senior lecturer in School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Malaysia. He received his Diploma in Forestry at Universiti Putra Malaysia, Bintulu Campus (UPMKB) and Sarawak, Malaysia from Mei 2009 to April 2012. In 2012, he was awarded the Public Service Department (JPA) scholarship to pursue his Bachelor’s Degree (BSc) in Chemical Engineering at University Putra Malaysia (UPM). Upon completing his BSc. programme in 2016, he was again awarded the Graduate Research Fellowship (GRF) by the Universiti Putra Malaysia (UPM) to undertake a PhD degree in the field of Biocomposite Technology & Design at Institute of Tropical Forestry and Forest Products (INTROP) UPM. R.A. Ilyas was the recipient of MVP Doctor of Philosophy Gold Medal Award UPM 2019, for Best PhD Thesis and Top Student Award.
Abstract:
Over the past decade, Nanocellulose has been proven to be one of the most prominent green materials of modern times. This renewable nanofiber has been used in wide range of applications from flexible packaging to advanced bio-scaffolds for tissue regeneration. The use of these renewable materials is important in future technologies. Nanocellulose have been the subject of decades of research due to their versatility and particularly their use in actuators, sensors, energy storage, space structure, membrane, packaging, automotive, and biomedical applications. Besides, Nanocellulose have found extensive application in smart hybrid systems, as nanocellulose can both contribute to the optical, thermal and mechanical properties of the system and bear stimuli-responsive surface modifications. In this presentation, we explain the outline of current development in this particular field, including the isolation, characterization, behaviour, and various applications of Nanocellulose reinforced polymer nanocomposites. The recent research on nanocellulose-containing smart hybrid systems will also be covered, with attention given to the fabrication methodologies that have been utilized. Besides that, we hope to impart the audience with some of the excitement that currently surrounds nanocellulose research, which ascends from the renewable source nature of the nanofiber, their fascinating, morphological, mechanical, chemical and physical properties, and the a variety of applications that can be developed from these nanomaterials. Besides that, the unique application of nanocellulose in shape memory polymers and self-healing nanocomposites will be deliberated.
Xiaodong Ma
Ã…bo Akademi University, Finland
Title: Combination of photothermal, prodrug and tumor cell camouflage technologies for triplenegative breast cancer treatment
Biography:
Xiaodong Ma began to study for a PhD at Abo Akademi University in 2020. His research includes functional biological nanomaterials, with an emphasis on prodrug synthesis, nanocarrier synthesis and related biological applications. During his research, Dr. Ma constructed several nano drug delivery vehicles based on stimulation-responsive mesoporous silicon dioxide nanoparticles (MSNs) and prodrug nanoparticles. By utilizing the stimulation characteristics of tumor microenvironment and external light source, Dr. Ma realized the controlled release of antitumor drugs, immunosuppressants and bioactive macromolecules to enhance the tumor treatment effect, paving the way for the application of prodrugs in the biomedical field
Abstract:
Traditional medicine has been widely uTriple-Negative Breast Cancer (TNBC) remains the most challenging breast cancer subtype. In the presented work, we have combined several emerging technologies to build up a nanoplatform for TNBC treatment: photothermal therapy, prodrug design and tumor cell camouflage formulation. First, we synthesized a paclitaxel (PTX) based prodrug PTX-SS, and then conjugated it to the surface of gold nanorod (Au NR) @ mesoporous silica (MSN) core-shell nanoparticles (Au@MSN-NH2 NPs). Subsequently, doxorubicin (DOX) was loaded into the Au@PTXSS-MSN NPs and further coated with cell membranes isolated from MDA-MB-231 cells to form cell camouflaged Au@PTXSS-MSN/DOX@CM NPs. The Au@PTXSS-MSN/DOX@CM NPs exhibited very good DOX loading capacity and the prodrug strategy enabled the precise adjustability of PTX-SS loading to achieve the optimized ratio between PTX and DOX to maximize the synergistic effect of these two drugs, as well as enabled GSH-responsive intracellular drug release. More interestingly, the cell membrane coating not only protected the drug from premature release, but also significantly improved the targeting ability of NPs to breast cancer MDA-MB-231 cells. The NPs also showed good photothermal responsiveness with clear improvement in inhibiting MDA-MB-231 cell proliferation under laser irradiation. The in vivo studies further confirmed the effectiveness of Au@PTXSS-MSN/DOX@ CM NPs on TNBC tumor inhibition in 4T1 cell grafted tumor mice model. Importance of Research: Triple-Negative Breast Cancer (TNBC) is the most aggressive breast cancer that is accompanied by poor prognosis and high rate of recurrence and metastasis. The using of targeted anticancer drugs (such as Herceptin, Lapatinib and Pertuzumab) has dramatically improved the prognosis of breast cancer; however, TNBC still lacks effective therapeutic drugs due to the lack expression of hormone receptors (include estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2), which are widely used for breast cancer targeting therapy. Cell camouflage technologies that utilize cancer cell originating cell membranes to hidden the drug carrier nanoparticles (NPs), have been found to be a good strategy for targeted cancer therapy owing to the extensive homology of the proteins and antigens between the cell membrane and cancer cells, as well as the homing ability of cancer cells. In summary, we have developed a new photothermal and GSH responsive NP with cell camouflage for targeted TNBC therapy. The Au NRs were embedded into the Au@PTXSS-MSN/DOX@CM with photothermal therapy activity, while the porous shell structure formed by MSN realized the high drug loading capacity to load the hydrophilic DOX. The prodrug technology enabled the PTX prodrug to have a GSH responsive linker and a conjugation site for conjugating onto the MSN. The coated cell membrane originating from tumor cells can protect the drugs from premature releasing and greatly improved the tumor targeting efficiency. Au@PTXSS-MSN/DOX@CM NPs have been confirmed to have good tumor cell targeting and synergistic anti-tumor effects at the cellular level. In addition, the Au@PTXSS-MSN/DOX@CM NPs also generated significant anti-tumor activity in vivo, as well as further improve the on-site drug release, for targeted TNBC therapy.